283例首治中晚期非小细胞肺癌患者证候要素研究

Study on Symdrome Factors of 283 Patients with Advanced Non-small Cell Lung Cancer

目的:探讨首治中晚期非小细胞肺癌患者证候要素分布特点。方法:采取回顾性调查方式对283例中晚期NSCLC患者进行中医四诊信息的采集,对临床症状体征进行因子分析和聚类分析。结果:因子分析提取8个因子(F),F1为痰湿证,F7为痰热证,F2、F3、F6均为阴虚证,F4为气虚证,F5、F8为血瘀证;聚类分析共聚为4类,经中医辨证分别为气虚证、阴虚证、痰证、血瘀证。结论:气虚证、阴虚证、痰证、血瘀证构成首治中晚期非小细胞肺癌患者的基本证候要素。

Objective：To study characteristics of syndrome Factors distribution in patients with advanced NSCLC. Methods：A clinical retrospective study was carried out in 283 patients with advanced NSCLC. We collected the information acquired through the four diagnostic methods and analyzed them in use of factor analysis and cluster analysis. Results ： Eight factors were selected through factor analysis. F1 was considered as phlegmatic hygrosis, F7 was Phlegm - Heat, F2,F3 ,F6 were yin asthenia, F4 was deficiency of QI, F5 ,F8 was blood stasis. Four clusters were obtained by cluster analysis, including deficiency of QI, yin asthenia, phlegm syndrome and blood stasis. Conclusion ： Basic symdrome factors of patients with advanced Non - small cell lung cancer include deficiency of QI, yin asthenia, phlegm syndrome and blood stasis.