SIRS评分预测重症监护病房患者发生医院感染与预后的研究

Systemic Inflammatory Response Syndrome Score Predicting Nosocomial Infection and Outcome in ICU Patients

目的探讨重症监护病房(ICU)患者全身炎症反应综合征(SIRS)评分与其发生医院感染及预后的相关性。方法记录1897例入住ICU的患者48 h内的SIRS评分,对其发生医院感染与预后进行前瞻性调查。结果共调查的1897例病例,发生医院感染191例,医院感染发生率10.1%;死亡188例,死亡率9.9%;例随SIRS评分分值的增加,医院感染发生率、患者死亡率有增加的趋势,且呈线性关系。结论SIRS评分作为一种简单、独立的评分方法,可初步预测ICU患者发生医院感染的危险性及其预后,提示早期实施干预措施防止医院感染发生和不良预后,具有重要的临床应用价值。

OBJECTIVE To study relativity of systemic inflammatory response syndrome （SIRS） score and nosocomial infection （NI） and outcome in ICU patients. METHODS A total of 1897 ICU patients were enrolled in our study. The SIRS within 48 hours after admission was recorded. And the prospective evaluation in NI and prognosis was made. RESULTS The nosocomial infection rate was 10.1%, and the mortality was 9.9%. With SIRS score increasing, NI and mortality rates increased as well and the tendency presented a linear correlation. CONCLUSIONS As a simple system, SIRS score can initially predict the risk of NI and outcome in ICU patients.