艾滋病患者医院真菌感染回顾性调查

Nosocominal Fungal Infection Status Among AIDS Patient: Investigation and Review

目的:调查与分析艾滋病患者医院真菌感染状况。方法:回顾性分析该院2005～2008年1463例AIDS患者真菌感染的临床资料。结果:1463例真菌感染部位以口咽部为主,占82.09%。真菌种类白色假丝酵母菌属占首位,为71.09%,其次是新型隐球酵母菌,占19.06%。住院时间、需要HAART治疗、使用广谱抗生素、侵袭性操作、抗真菌的不规范治疗是真菌感染的危险因素。结论:控制感染的危险因素,合理使用抗生素,减少侵入性操作,提高患者机体的免疫力是预防艾滋病患者真菌感染的主要措施。

Objective： To investigate and analyze the status of nosocominal fungal infection among AIDS patients. Methods： We reviewed and analyzed clinical data of 1463 AIDS patient in our hospital from 2005 to 2008. Result： Inthe 1463 case of fungal infections, 82.09% of them were Oropharyngeal infection.Candida tropicalis, was most common （71.09%）, then Cryptococcus （19.06%）. Hospital-stay time, HAART treatment, use of broad-spectrum antibiotics, invasive operation, and non-standard anti-fungal treatment were major risk factors of fungal infection. Conclusion： Control the risk factors, properly antibiotic use. reducing invasive operation and improving patient＇s immunity are major effective ways to prevent fangal infection in AIDS patients.