舒芬太尼用于老年心脏病病人非心脏手术后镇痛的疗效观察

The Effect of Sufentanil on Postoperative Analgesia in Geriatric Patients Noncardiac Surgery

目的:探讨舒芬太尼在老年心脏病病人非心脏手术术后静脉自控镇痛的效果。方法:40例择期全麻下开腹手术的老年患者,随机分为舒芬太尼组(SF组)和芬太尼组(F组),每组20例。SF组术后镇痛以舒芬太尼2μg/kg,F组术后镇痛以芬太尼25μg/kg,均用生理盐水稀释至100ml。记录病人术后4h、12h、24h时疼痛评分、镇静评分和舒适程度评分、脉搏氧饱和度(SpO_2)、PCA有效按压情况,以及恶心、呕吐的发生情况。结果:舒芬太尼组术后4h、12h、24h的疼痛评分明显低于芬太尼组(P<0.05),镇静评分、舒适评分高于芬太尼组;术后4h、12h、24h时点间舒芬太尼组的按压次数明显少于芬太尼组;SpO_2在两组间无明显差别。结论:舒芬太尼是一较好的术后静脉镇痛药物,可用于术后病人静脉自控镇痛。

Objective：To investigate the effect of sufentanil on postoperative patient controlled intravenous analgesia in geriatric patients noncardiae surgery.Methods：Forty patients with abdomen surgical operation under general anesthesia were divided randomly into two groups,sufentanil group（SF group,n=20） and fentanyt group（F group,n=20）.SF group used sufentanil 2-3μg/kg and F group used fentanil 25μg/kg,the drugs used were diluted in 100ml normal saline for patient controlled intravenous analgesia.The visual analogue scale,sedation score,comfort level scale,blood oxygen saturation,patient effective press quantity and incidences of nausea,vomiting were recorded 4h, 12h,24h after the analgesia.Results：Compared with F group, the visual analogue scale was reduced significantly in SF group 4h,12h,24h after the analgesia（P〈0.05）,the sedation score and comfort level scale were higher in SF group.The quantity of patient effective press in SF group were lesser than SF group,and the blood oxygen saturation were similar between the two groups.Conelusions：Sufantanil is a better drugs for patient controlled intravenous analgesia.