经咽鼓管鼓室内地塞米松注射治疗突发性聋

Pharyngotympanic tube intratympanic dexamethasone injections for sudden sensorineural hearing loss

目的观察经咽鼓管鼓室注入地塞米松治疗突发性聋(突聋)的疗效。方法对20例常规方法治疗无效的突聋患者采用经咽鼓管鼓室径路注入地塞米松,1次/周,每次5mg,共3次。用药期间密切观察记录听力改变、耳鸣和眩晕等情况。结果20例患者于治疗完成后一周复查纯音测听。显效8例,0.25～4kHz听阈平均提高35.4dB;有效1例,平均提高14dB;无效11例;有效率为45%。结论鼓室内应用激素能改善常规治疗无效的突发性聋患者的听力。为常规方法治疗无效的突聋患者提供了再次治疗的机会。

Objective To investigate the efficacy of pharyngotympanic tube intratympanic dexamethasone injection for patients with sudden sensorineural hearing loss （SSNHL）. Methods Dexamethasone （5 mg） was injected into the middle ear of 20 patients with SSNHL via the pharyngotympanic tube. The injection was repeated every week for a total of 3 doses. Results After one-week follow-up nine of the 20 patients （45%） improvement in PTA and the remaining 11 （55%） had no response. Conclusion Pharyngotympanie tube intratympanic dexamethasone injection is a simple and effective treatment for SSNHL. It provides an opportunity to cure refractory SSNHL.