亚甲蓝肋间毁损在胸部手术后的止痛作用

Methylene blue in the chest damaged intercostal post-operative analgesic effect

目的探讨胸部手术后止痛的新方法。方法对60例开胸手术患者随机均分两组,实验组:在胸部手术结束关胸前,在胸椎侧开胸肋间及上下各一肋间注入亚甲蓝。对照组:在周围静脉置止痛药泵。术后采用视觉模拟评分法(visual analogue scales,VAS)评价两组止痛效果。结果术后6h、12h、24h、48h、72h两组疼痛VAS评分实验组与对照组无显著性差异(P>0.05)。药物不良反应实验组低于对照组,其差异有统计学意义(P<0.05)。术后并发症实验组低于对照组,其差异有统计学意义(P<0.05)。结论亚甲蓝肋间神经毁损预防开胸术后疼痛具有简单易行,持续时间长,术后并发症少,无毒副作用的特点。

Objective The aim is to explore the new methods of acesodyne after the operation. Methods 60 eases of patients with thoracic surgery were randomly divided into two groups, experimental group ： beore the end of chest surgery, respective injection of methylene blue between the sternal ribs. and upper and lower in- tercostal muscles in the thoracic spine lateral thoraeotomy. Control group ： implantation of painkiller pump in the peripheral venous. After operation, take the use of visual analogue score （visual analogue scales, VAS） to evaluate the analgesic effect of the two groups. Results VAS pain scores of postoperative 6 h, 12 h ,24 h ,48 h,72 h show no significant difference （ P 〉 0. 05 ） between the experimental group and the control group. Adverse drug reactions of the experimental group is fewer than of the control group, and the difference is statistically significant （ P 〈 0.05 ）. Complications of the experimental group are also fewer than of the control group, and the difference is statistically significant. Conclusion The injection of methylene blue through damaging intercostal nerve is to inhibit pain after thoracotomy, The characteristics of the method is simple, long-duration, less post-operative complications, non-toxic and side effects.