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地塞米松用于硬膜外吗啡镇痛时引起恶心呕吐的预防

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摘要 目的观察地塞米松用于硬膜外注入吗啡镇痛时引起恶心呕吐(PONV)的预防效果。方法选择40例手术患者,并分为对照组和实验组,于术毕把预定剂量吗啡1.5mg+0.25%布比卡因5ml+氟哌利多2mg注入硬膜外腔,同时静脉注射生理盐水2ml(对照组,n=20)和地塞米松10mg(实验组,n=20)。观察两组患者发生PONV、皮肤瘙痒和镇痛效果的情况。结果发生PONV者,对照组6例、实验组3例,组间相比存在明显差异性(P<0.05);发生皮肤瘙痒者,组间相比无明显差异性(P>0.05);两组对镇痛效果均较满意。结论地塞米松预防吗啡镇痛时引起PONV,具有一定疗效,且价格便宜,值得临床推广应用。
出处 《中国实用医药》 2009年第33期118-119,共2页 China Practical Medicine
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