益气生骨注射液促进体外成肌细胞增殖作用的研究

Effect of Yiqi Shenggu Parenteral Solution on in vitro Proliferation of Myoblasts

目的:研究益气生骨注射液对体外培养的成肌细胞的增殖作用。方法:将成肌细胞进行体外培养,实验组加入不同浓度的益气生骨注射液,对照组分别加入不同浓度的黄芪注射液和复方当归注射液,空白组不加任何药物。筛选出各药物对细胞增殖的最适生长浓度,并观察其对细胞的增殖作用。结果:益气生骨注射液对成肌细胞的增殖作用最强,与空白组比较,差异有统计学意义(P<0.05),与对照组比较,差异无统计学意义。结论:益气生骨注射液有促进成肌细胞增殖的作用。

Objective：To research the effect of Yiqi Shenggu parenteral solution on in vitro proliferation of myoblast. Methods：Yiqi Shenggu parenteral solution was compared with Huangqi parenteral solution, Compound Angelica parenteral solution and blank group on cultured myoblasts at various concentrations. The optimal growth concentration of myoblasts proliferation was filtered for each parenteral solution and their impacts on proliferation were observed. Results： Not statistically different with other two medicated solutions, Yiqi Shenggu had significant stimulating effect than the blank group （P 〈 0. 05 ）. Conclusion ： Yiqi Shenggu parenteral solution can promote the proliferation of myoblasts.