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人绝经期促性腺激素联合宫腔内人工授精治疗多囊卵巢综合征不孕47例 被引量:1

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摘要 目的:观察人绝经期促性腺激素(human menopausal gonadotropins,hMG)联合宫腔内人工授精(intrauterine insemination,IUI)治疗多囊卵巢综合征(polycystic ovary syndrome,PCOS)不孕的疗效。方法:取47例PCOS不孕的患者,予hMG低剂量递增促超排卵,1~2个直径≥18 mm的卵泡出现后,肌肉注射绒毛膜促性腺激素(human chorionic gonadotropin,hCG)1万IU,48 h内每日行IUI 1次,并支持黄体,12天后查血hCGβ亚单位,确定是否妊娠,未妊娠者下周期同法治疗。结果:112周期排卵率86.6%,周期妊娠率31.3%,患者妊娠率74.5%。妊娠组治疗平均周期(2.7±1.5)个,高于非妊娠组治疗平均周期(1.7±0.8)个(P〈0.01)。结论:hMG联合IUI治疗PCOS不孕疗效显著,治疗周期较多者,妊娠率愈高。
作者 耿鹏
出处 《蚌埠医学院学报》 CAS 2009年第11期1000-1001,共2页 Journal of Bengbu Medical College
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参考文献4

  • 1CedarsMI.不孕症[M].北京:人民卫生出版社,2006:193.
  • 2SperoffL,GlassRH,KaseNG主编.临床妇科内分泌学与不孕[M].第6版.济南:山东科学技术出版社,2003:811-812.
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二级参考文献5

  • 1World health Organization. Collection and examination of human semen. In: WHO laboratory manual for the examination of human semen and sperm-cervical mucus interaction. 4th eds. Coimbridge: Cambridge University Press, 1999.4-5.
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