肾动脉化疗栓塞术在肾癌根治性切除术前的临床应用

Clinical application of chemotherapeutic renal artery embolization before radical nephrectomy in treatment of renal carcinoma

目的:探讨肾癌根治性切除术前行肾动脉化疗栓塞术的临床应用价值。方法:对17例肾癌患者,在根治性切除术前采用碘化油和明胶海绵等在数字减影血管造影监视下行肾动脉化疗栓塞。结果:17例术前肾动脉检塞术均成功实施。术中肿瘤易于剥离,手术野清晰,出血量少。病理可见肿瘤坏死明显,与周围组织界限清楚。结论:肾动脉栓塞治疗是一种安全、有效的肾癌治疗方法。肾癌根治术前行肾动脉化疗性栓塞可明显减少围手术期风险,值得临床推广。

Objective： To assess the clinical value of chemotherapeutic renal artery embolization before radical nephrectomy in treatment of renal carcinoma. Methods：Clinical data were retrospectively analyzed in 17 cases of renal carcinoma who were treated with chemotherapeutic renal artery embolization by uhraliquified iodipin and gelatin sponge under digital subtraction angiography （DSA） before radical nephreetomy. Results：Seventeen cases the preoperative embolizations of renal artery were successfully perforuled. After renal artery embolization, the surgical resections revealed that the operation field was clear, the lumps were easily to peel off with less bleeding. The histopathology demonstrated that the tumors had obvious necrosis and the borderline with peripheral normal tissues was clear. Collehlsions：Embolization of renal artery is effective and safe in treatment of renal carcinoma. Chemotherapeutic renal artery embolization before radical uephrectomy in renal carcinoma can greatly decrease the risk in the operation. Renal artery embolization shoud be widely applied for renal carcinoma.