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呼气末正压通气对重型颅脑损伤术后患者颅内压及脑灌注压的影响 被引量:2

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摘要 目的研究呼气末正压通气(PEEP)对重型颅脑损伤术后患者颅内压(ICP)及脑灌注压(CPP)的影响。方法选取监护病房内22例重型颅脑损伤术后呼吸机辅助呼吸的患者,记录不同PEEP下(4 mm Hg、8 mm Hg、12 mm Hg)的ICP、平均动脉压(MAP)、CPP,研究其变化及相互关系。结果 PEEP升高后ICP的变化无统计学差异,PEEP为12 mm Hg时CPP的降低有统计学意义。部分患者ICP、CPP变化明显,与MAP降低有关。结论 PEEP升高至12 mm Hg不会明显的影响ICP,ICP、CPP的变化受MAP变化的影响,在保持MAP稳定的前提下,使用PEEP是安全的。
出处 《中国医学创新》 CAS 2009年第33期70-71,共2页 Medical Innovation of China
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