旋毛虫成囊前期幼虫排泄分泌抗原的研究进展

Progress on excretory-secretory antigens of Trichinella spiralis pre-encysted larva

在旋毛虫感染过程中,成囊前期幼虫(PEL)是旋毛虫侵入宿主肌肉的侵入期。旋毛虫PEL比成囊期幼虫(EL)在宿主体内约早2周出现。成囊前期幼虫抗原(PELA)对旋毛虫病的早期免疫学诊断具有较高的敏感性。而旋毛虫排泄分泌抗原具双重免疫功能,即有良好的抗原性和免疫原性。因此,本文就旋毛虫成囊前期幼虫ES抗原研究进展做一综述。

The pre-encysted larvae is the period of invasive hosts muscle in the development of Trichinella spiralis. T. spiralis pre-encysted larvae than encysted larva appeared about two weeks early in hosts. The pre-encysted larva antigens of T. spiralis have high sensitivity in the eary diagnosis of immunization. And excretory-secretory antigen of T. spiralis has double immune function, that is good antigenicity and immunogenicity. Therefore, this article introduced the progress on excretory-secretory antigens of T. spiralis pre-encysted larva.