炎症性肠病的胃肠动力学改变

Dynamics change in gastrointestinal tract of inflammatory bowel disease

炎症性肠病(inflammatory bowel disease,IBD)是一种原因不明的顽固性难治的慢性非特异性肠炎,主要包括溃疡性结肠炎(ulcerative colitis,UC)和克罗恩病(Crohn’s disease,CD)。它的发病在我国呈逐渐上升的趋势,然而其病因和发病机制尚不明确。目前认为它是环境、遗传、病原体和机体免疫等多因素相互作用失衡产生的疾病。IBD的特点之一是慢性肠道炎症伴随有动力方面的改变。近年来,关于IBD与肠道动力之间关系的研究已经受到越来越多的关注,并已成为IBD发病机制研究的一大热点。

Inflammatory bowel disease is an agnogenic,refractory and chronic nospecific intestinal inflammation,including ulcerative colitis and Crohn＇s disease.Its incidence in our country shows an upward trend year after year,but its etiology and pathogenesis are not clear.At present,we think it is a disease resulting from imbalance in the interaction of environment,genetics,pathogens and immune factors.One of IBD＇s characteristics is the chronic intestinal inflammation accompanied by changes in motility.In recent years,the research in the relationship of IBD and intestinal motility has become more and more popular,and the pathogenesis of IBD has become a hot research.