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FDG PET-CT在食管癌放疗靶区勾画中的作用 被引量：6

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摘要 食管癌三维适形放疗使高剂量分布的形状在三维方向上与病变（靶区）的形状一致，在最大程度上杀灭肿瘤细胞的同时尽量保护周围正常组织和器官。FDGPET技术可利用正电子核素标记葡萄糖可以发现癌细胞，而且常在肿瘤组织形态、结构改变之前就能发现代谢异常，因而能早期发现肿瘤；在发现远处转移方面其敏感性也要远高于CT。本研究目的在于研究PET与CT图像融合在食管癌三维适形放疗中靶区勾画中的作用。
作者 任瑞美 付正 于金明 张永明 张国芬 赵献光
机构地区 山东省肿瘤医院放疗科放二科
出处 《中华放射肿瘤学杂志》 CSCD 北大核心 2009年第6期429-430,共2页 Chinese Journal of Radiation Oncology
关键词 PET-CT 放疗靶区 食管癌 FDG 三维适形放疗 正电子核素标记 肿瘤细胞 PET技术
分类号 R686 [医药卫生—骨科学]
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参考文献6

  • 1Nishioka T, Shiga T, Shirato H, et al. Image fusion between ^18FDG-PET and MRI/CT for radiotherapy planning of oropharyngeal and nasopharyngeal carcinomas. Int J Radiat Oncol Biol Phys ,2002,53 : 1051-1057.
  • 2Moureau-Zabotto L, Touboul E, Lerouge D, et al. Impact of CT and ^18F-deoxyglucose positron emission tomography image fusion for conformal radiotherapy in esophageal carcinoma. Int J Radiat Oncol Biol Phys,2005,63:340-345.
  • 3Vrieze O, Haustermans K, De Wever W, et al. Is there a role for FGD-PET in radiotherapy planning in esophageal carcinoma? Ra-diother Onco1,2004 ,73 :269-275.
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同被引文献48

  • 1张书旭,王兆武,沈国辉,谭剑明,林生趣.鼻咽癌调强放疗受照剂量分布特性研究[J].肿瘤基础与临床,2006,19(3):203-205. 被引量：6
  • 2袁双虎,于金明,于甬华,杨新华,付政,杨国仁,郭洪波,王晓航,周英智,陈少卿.^(18)F-脱氧葡萄糖PET-CT检测食管癌病变长度的临床价值[J].中华放射肿瘤学杂志,2006,15(5):389-392. 被引量：46
  • 3郭洪波,于金明,张百江,朱慧,张为迪,李玲,黄勇,付政,李辉.氟脱氧葡萄糖PET—CT确定食管癌淋巴结放疗靶区的可行性研究[J].中华放射肿瘤学杂志,2007,16(1):10-14. 被引量：18
  • 4Kauhanen SP, Komar G, Seppanen MP, et al. A prospective diagnostic accuracy study of ^18F - fluorodeoxy glucose positron emission tomography/eomputed tomography, multidetector row computed tomography, and magnetic resonance imaging in primary diagnosis and staging of pancreatic cancer. Ann Surg, 2009,250 : 957-963.
  • 5Bilimoria KY, Bentrem D J, Ko CY, et al. Validation of the6th edition AJCC pancreatic cancer staging system report from national cancer database. Cancer,2007,110:738-744.
  • 6Mukund S, Didolkar-Cardella W, Coleman-Mark J. Image-guided stereotactic radiosurgery for locally advanced pancreatic adenocarcinoma results of first 85 patients. J Gastmintest Surg, 2010,14 : 1547-1559.
  • 7Casneuf V, Delrue L, Kelles A, et al. Is combined ^18F- fluorodeoxy glucose-positron emission tomography/computed tomography superior to positron emission tomography or computed tomography alone for diagnosis, staging and restaging of pancreatic lesions? Acta Gastroemerol Belg,2007,70:331-338.
  • 8Van Laere K, Ceyssens S, comparison of IS F-FDG and Van Calenbergh F, et al. Direct 11C-methionine PET in suspected recurrence of glioma: sensitivity, inter-observer variability and prognostic value. Eur J Nucl Med Mol Imag.2005.32:39-51.
  • 9Fox JL, Rengan R, O'Meara W, et al. Does registration of PET and planning CT images decrease interebserver and intraobserver variation in delineating tumor volumes for non-small-cell lung cancer? Int J Radiat Oncol Biol Phys,2005,62:70-75.
  • 10Topkan E, Yavuz AA, Aydin M, et al. Comparison of CT and PET-CT based planning of radiation therapy in locally advanced pancreatic carcinoma. J Exp Clin Can Res,2008,27:27-41.

引证文献6

二级引证文献36

中华放射肿瘤学杂志
2009年 第6期

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