准分子激光原位角膜磨镶术后干眼和屈光回退的相关性(英文)

Correlation between dry eye and refractive regression after laser in situ keratomileusis

目的:探讨准分子激光原位角膜磨镶术后干眼和屈光回退的相关性。方法:近视患者225例分别在LASIK术前及术后6mo进行Schirmer试验、泪膜破裂时间、角膜知觉和角、结膜荧光素染色检查,并接受McMonnies问卷调查。综合病史及治疗效果对结果作比较分析。结果:LASIK术后干眼和屈光回退显著相关。术后发生干眼症的32例患者中8例(25.0%)同时伴有屈光回退,而未发生干眼症的193例患者中仅18例(9.3%)伴有屈光回退,差异有极显著意义(P<0.01)。结论:LASIK术后干眼患者屈光回退的危险性增加。

AIM：To investigate the correlation between chronic dry eye and refractive regression after laser in situ keratomileusis（LASIK） for myopia.·METHODS：Two hundred and twenty-five eyes of 225 patients were enrolled in this study.Examinations including Schirmer test,tear break-up time（BUT）,corneal sensation,and ocular surface staining were performed before and 6 months after LASIK.Dry eye symptoms were assessed using the McMonnies Dry Eye Symptom Survey.Data were analyzed on history and treatment response.·RESULTS：Refractive regression after LASIK was related to chronic dry eye.It occurred in 8（25.0%） of 32 patients with chronic dry eye and in 18（9.3%）of 193 patients without dry eye（P〈0.01）.·CONCLUSION：The risk of refractive regression was increased in patients with chronic dry eye.