超声生物显微镜评价Nd:YAG激光治疗临床前期闭角型青光眼

Evaluation of Nd:YAG laser for the treatment of pre-clinical angle-closure glaucoma by ultrasound biomicroscopy

目的:应用超声生物显微镜观察急性闭角型青光眼的对侧眼行激光周边虹膜切除术的有效性。方法:72例72眼急性闭角型青光眼的对侧眼行Nd:YAG激光预防性激光周边虹膜切除术,激光治疗前后应用超声生物显微镜(ultrasound biomicroscopy,UBM)观测前房深度(anterior chamber depth,ACD)、房角开放距离500(angle o-pening distance,AOD500)和前房角开放度数(anterior angle,AA)。结果:患者术后前房深度、房角开放距离和前房角开放度数明显大于术前,术后1wk的ACD,AOD500,AA与术前相比有显著性差异(P<0.01)。结论:激光周边虹膜切除术对于无广泛房角粘连和关闭的临床前期闭角型青光眼有预防发作和治疗作用,使用Nd:YAG激光安全可靠。

AIM：To observe the efficacy of laser peripheral iridectomy in the fellow eyes of acute angle-closure glau-coma eye by ultrasound biomicroscopy.·METHODS：Seventy-two patients（72 eyes） with acute angle-closure glaucoma underwent Nd：YAG laser preventive laser peripheral iridectomy in the contralateral eyes.Before and after the application of ultrasound biomicroscopy（UBM）,anterior chamber depth（ACD）,angle opening distance（AOD500）,and opening degrees of anterior angle（AA） were observed.·RESULTS：Postoperative anterior chamber depth,distance and degrees of angle opening were significantly greater than those before surgery.ACD,AOD500 and AA one week after operation compared with the preoperative had significant differences（P〈0.01）.·CONCLUSION：Laser peripheral iridectomy for the treatment of non-wide angle adhesion and closure of pre-clinical angle-closure glaucoma can prevent attack and have therapeutical effect,and the use of Nd：YAG laser seems to be safe and reliable.