郑州市正常新生儿脑组织氧饱和度正常参考值范围的研究

Study on range of normal reference value of cerebral oxygen saturation in healthy neonates in Zhengzhou city

目的：探讨近红外光谱测定技术（near—infrared spectroscopy，NIRS）检测正常新生儿局部脑组织氧饱和度（regional oxygen saturation，rSO2），建立新生儿脑rSO2的正常值参考值范围。方法：应用TSAH-100型近红外组织血氧参数无损监测仪，测定我院正常新生儿出生后1、2、3、10～15天时的脑组织氧饱和度变化，并进行比较。结果：正常新生儿脑rSO2在出生后第1天为（62．02±2．86）％、第2天为（62．06±2．40）％、第3天为（61．91±2．29）％、第10天后为（61．96±2．40）％，比较差异无统计学意义（P〉0．05）；不同性别正常新生儿的rSO2在出生后第2、3、10天比较差异有统计学意义（P〈0．05）；rSO2与SPO2总体呈正相关。结论：郑州市正常足月新生儿脑rSO2测定值参考范围为（62．03±2．51）％，如果低于57．9％则提示有脑组织缺氧。

Objective： To establish range of normal reference value of cerebral oxygen saturation in healthy neonates by detecting regional cerebral oxygen saturation （ rSO2 ） using near - infrared spectroscopy. Methods ： The changes of rSO2 of healthy neonates were detected by TSH - 100 near infrared speetrophotometry human tissue oximeter at the 1, 2, 3, 10 - 15 days after birth, then the results were compared. Results： The rSO2 values at the 1, 2, 3, 10 - 15 days after birth were （62.02 ±2.86）% , （62.06 ±2.40）% , （61.91 ± 2.29） % and （61.96 ± 2.40）% , respectively, there was no significant difference; there was significant difference in rSO2 values at the 2, 3, 10 days between boys and girls （ P 〈 0. 05 ） ; there was positive correlation between rSO2 and SpO2. Conclusion： The range of normal reference value of rSO2 in healthy neonates in Zhengzhou city is （62. 03 ± 2. 51 ） % , normal reference value 〈 57.9% indicates hypoxia of brain tissue.