单眼视网膜静脉阻塞患者对侧眼黄斑功能的多焦视网膜电图检测

Multifocal electroretinogram of the fellow eye in patients with unilateral retinal vein occlusion

目的 观察单眼视网膜静脉阻塞（RVO）患者对侧眼黄斑功能的变化。方法 对比分析24例经荧光素眼底血管造影（FFA）确诊为单眼RVO患者的24只对侧眼及18位正常受试者18只正常眼的多焦视网膜电图（mfERG）检测结果，比较两组受试者黄斑功能的差异。采用罗兰RETIscan电生理仪记录mfERG，将记录图形分别按照6个同心圆和4个象限对P1、N1波的振幅密度及潜伏期进行比较和分析。结果 RVO患者对侧眼在中心第1、2环处P1、N1波的振幅密度显著低于正常眼，差异有统计学意义（t=4.520,2.147；P〈0.05）；其它各环、各象限振幅密度及潜伏期在两组间均未见明显差异（P〉0.05）。结论 与正常眼相比，RVO患者对侧眼黄斑中心凹视功能受损。

Objective To measure the macular function of the fellow eye in patients with unilateral retinal vein occlusion （RVO）. Methods A total of 24 cases of unilateral RVO were diagnosed by fundus fluorescein angiography （FFA）, and multifocal ERG （mfERG） was recorded by RETI scan. The mfERG data of 24 fellow eyes of those RVO patients, and 18 normal control eyes were analyzed and compared. The parameters included the amplitude density, latency of the P1 and N1 wave in 6 concentric circles and 4 quadrants of the mfERG graphics. Results The amplitude densities of P1 and N1 wave in first and second concentric circles of RVO fellow eyes were significantly lower than normal eyes （t=4.520, 2.147; P〈0.05）. There was no significant difference （P〉0.05） of P1/N1 latency in any concentric circles or quadrants between RVO fellow eyes and normal eyes. Conclusion The central fovea of the RVO fellow eyes was functionally impaired.