术中应用瑞芬太尼维持麻醉患者术后的疼痛管理

The management of postoperative analgesia after introperative remifentanil-based anaesthesia.

瑞芬太尼是芬太尼家族中最年轻的成员。瑞芬太尼最吸引人的特性就是快速起效和作用快速消除，且不依赖输注时间的长短和任何器官的功能。因此，在要求快速起效或作用快速消除时，瑞芬太尼成为最佳选择。这样可以明显缩短插管和拔管时间。由于在停用瑞芬太尼后镇痛作用也很快消失。因此需要预先处理停用瑞芬太尼后的疼痛问题。

Remifentanil, one of the anilidopiperidine family, is probably the most original. Remifentanil has a unique pharmacokinetic profile that combines a short onset and the fastest elimination, independent of the infusion duration or any organ insufficiency. Consequently, it offers a unique titratability when its effects need to be quickly achieved or eliminated. This may permit both a significant reduction in weaning and extubation times. The absence of any residual analgesic effects after remifentanil-based anesthesia means that measures must be taken to prevent pain before the remifentanil infusion is discontinued.