鲜红斑痣的病因研究进展

Etiology of port wine stains

鲜红斑痣是好发于婴幼儿面颈部的血管性疾病，可随着年龄的增长逐渐发展，严重影响患者的心身健康，确定其病因可以预防及治疗鲜红斑痣。鲜红斑痣的可能病因包括皮损处血管周围神经减少、血管周围支持结构减少、胚胎发育过程中细胞因子改变、基因异常以及外伤等获得性因素。它也可能是一组临床症状的表现之一。然而目前这些研究仍处于较初始的阶段，今后需要深入地研究来明确鲜红斑痣的确切病因。

Port wine stains （PWS）, which are typically located on the face and neck of infants, may enlarge and darken with age, and severely influence the psychological and physical health of patients. To explore the etiology of PWS is beneficial to its prevention and treatment. The possible etiology of PWS includes the decrease of nerve density and supporting structure around blood vessels, changes of cytokines in embryonic development, gene abnormality, trauma, etc. Also, it may be one of clinical manifestations of a syndrome. However, these kinds of studies are still in initial stage, further studies are needed to learn the exact etiology of PWS.