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代谢组学在药物安全性评价中的应用进展 被引量:2

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出处 《毒理学杂志》 CAS CSCD 北大核心 2009年第5期415-418,共4页 Journal of Toxicology
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  • 1Nicholson JK, Lindon JC, Holmes E. ' Metabonomics ' : understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data [ J ]. Xenobiotica, 1999, 29: 1181-1189.
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  • 7Sun JC, Schnackenberg LK, Holland RD, et al. Metabonomics Evaluation of Urine from Rats Given Acute and Chronic Doses of Acetaminophen Using NMR and UPLC/MS [J]. J Chromatogr B, 2008, 84: 207-277.
  • 8Yap IK, Clayton TA, Tang H, et al. An Integrated Metabonomic Approach To Describe Temporal Metabolic Disregulation Induced in the Rat by the Model Hepatotoxin Allyl Formate[J]. J Proteome Res, 2006, 5: 2675-2684.
  • 9Huang X, Shao L, Gong W, et al. A metabonomic characterization of CCl4-induced acute liver failure using partial least square regression based on the GC/MS metabolic profiles of plasma in mice[J]. J Chromatogr B, 2008, 870: 178-185.
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