增精1号胶囊对少精子症患者精子动态及形态的影响

Effect of Zengjing No.1 Capsule on Morphology and Motility of Sperm in Patients with Oligospermia

目的探讨增精1号胶囊对少精子症患者精子动态及形态的影响。方法将72例患者按随机数字表法分为治疗组(30例)和对照组(31例),分别给予增精1号胶囊和五子衍宗丸口服,于服药前及服药3个月后,取精液以改良巴氏染色法将精子染色后采用WLJY-9000伟力彩色精子质检计算机辅助精液分析系统(CASA)检测精子密度、活力及形态变化。结果增精1号胶囊治疗组精子密度、活力均较治疗前明显提高(P<0·01),精子畸形率降低(P<0·01),且优于五子衍宗丸对照组(P<0·01)。结论增精1号胶囊可改善少精子症患者的精子密度、活力,降低精子畸形率。

Objective To explore the effect of Zengjing Capsule No. 1 （ZJC1） on morphology and motility of sperm in patients with oligospermia （OSM）. Methods Seventy-two OSM patients were assigned to 2 groups by; a randomizing digital table, the treated group and the control group, they were treated respectively by ZJC1 and Wuzi Yanzong Pill （WYP）. The changes of density, motility and morphology of sperm in patients be- fore and after 3-month treatment were examined using computerized WLJY-9000 colour semen analysis system with refined Papanicolaou＇s stain. Results The density, motility and morphology of sperm were improved and sperm deformity rate was significantly decreased after treatment in both groups （ P 〈0.01 ）, but the effects in the treated group were better than those in the control group （ P 〈0.01 ）. Conclusion ZJC1 can enhance the density and motility of sperm and reduce the sperm deformity rate in patients with OSM.