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MIF、MMP-9、ISO-1与大肠癌的关系

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摘要 MIF刺激大肠癌细胞的增殖、分化以及抑制肿瘤细胞的凋亡,MMP-9促进大肠癌血管的生成和肿瘤细胞增殖,促进肿瘤侵袭与扩散,ISO-1通过抑制MIF互变异构酶活性、降低了MMP-9表达,从而抑制大肠癌细胞的增殖、浸润。
作者 秦冰 瞿峰
出处 《现代肿瘤医学》 CAS 2009年第11期2245-2246,共2页 Journal of Modern Oncology
基金 河北省邯郸市科技局科研项目(编号:200610808-8)
关键词 MIF MMP-9 ISO-1 大肠癌
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