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肺血栓栓塞症溶栓治疗时间窗的探讨与商榷 被引量:5

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摘要 随着诊断意识和检查技术水平的不断提高,肺血栓栓塞症(pulmonary thromboembolism,PTE)的检出率也逐渐升高,目前PTE的防治已经成为全球重要的医疗保健问题。溶栓疗法通过药物直接或间接将血浆蛋白纤溶酶原转变为纤溶酶,迅速裂解纤维蛋白,使血块溶解,同时因此引起纤维蛋白和纤维蛋白酶原降解产物增多又可抑制纤维蛋白原向纤维蛋白转变并干扰纤维蛋白聚合,从而发挥抗凝效应。理想的溶栓药应具备:迅速纠正心功能不全;避免大出血;适应证明确;使用方便和价格低廉。溶栓是治疗PTE过程中的一个重要措施,
出处 《中华结核和呼吸杂志》 CAS CSCD 北大核心 2009年第11期852-853,共2页 Chinese Journal of Tuberculosis and Respiratory Diseases
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