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右半肝活体肝移植中肝中静脉的应用

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摘要 活体肝移植(LDLT)的发展不仅在一定程度上缓解了器官短缺引发的矛盾,而且具有供肝来源,质量高、排异轻、预后较好和费用低等优点,因此逐渐被人们重视。在一些知名的移植中心,LDLT已占到肝脏移植手术的50%左右,受体1年生存率超过90%,2年生存率超过85%。近年来,采用右半肝进行成人间活体肝移植被广泛接受,成为目前活体肝移植的主要术式,但是对成人有半肝移植是否保留供肝的肝中静脉(MHV)一直存在争论㈤。通常认为移植物与受者体质量比(GRWR)应在1%以上,移植物与受者标准肝体积比(GV/SLV)应在50%以上,才能满足受者需要,为保证受者获得足够的肝脏,供肝切取应采用包含MHV的右半肝;但从保证供体安全的角度考虑,MHV最好保留在供者体内。
作者 潘澄 沈中阳
出处 《天津医药》 CAS 北大核心 2009年第11期988-991,共4页 Tianjin Medical Journal
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