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氟比洛芬酯复合芬太尼用于胆囊切除术自控静脉镇痛效果的观察 被引量:1

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摘要 目的观察氟比洛芬酯复合芬太尼用于胆囊切除术自控静脉镇痛(PCIA)的疗效。方法ASAⅠ~Ⅱ级择期行胆囊切除术的患者80例,依据术后镇痛方案的不同随机分为A、B、C、D4组,每组20例,A组:芬太尼15μg/kg;B组:氟比洛芬酯100mg+芬太尼12μg/kg;C组:氟比洛芬酯100mg+芬太尼9μg/kg;D组:氟比洛芬酯100mg+芬太尼6μg/kg,各组均加0.9%氯化钠溶液稀释至100ml。术后使用电子镇痛泵行PCIA,定时行疼痛视觉模拟评分(VAS),记录自控镇痛按压次数和不良反应发生情况。结果术后2h、4h,A、B、C组的VAS低于D组(P<0.05),PCA按压次数,A、B、C组少于D组(P<0.05),恶心、呕吐、嗜睡的发生率A、B组高于C、D组(P<0.05)。结论氟比洛芬酯复合芬太尼用于胆囊切除术PCIA,效果确切,可减少芬太尼用量40%左右,同时明显降低了不良反应发生率,是安全、有效的一种镇痛方法。
出处 《河北医药》 CAS 2009年第19期2587-2588,共2页 Hebei Medical Journal
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