三维适形同步TP方案治疗食管癌放疗后复发疗效观察

clinical study of three dimensional conformal radiotherapy combined with chemotherapy for recurrent esophageal carcinoma after radical radiotherapy

目的:观察放疗后复发食管癌患者适形放疗联合化疗的疗效。方法:2005年10月-2006年12月对38名患者采用适形放疗联合化疗。结果:CR23例(60.5%),PR11例(28.9%),SD2例(5.26%),PD2例(5.26%)。1、2年生存率分别为60.5%、34.2%。死亡原因为局部未控12例(31.6%),远处转移13例(34.2%)。结论:对食管癌放疗后复发患者采用适形放疗联合化疗,可提高局控率,有望提高生存率。

Objective：To investigate the effects of three dimensional conformal radiotherapy （3 - DCRT） combined with chemotherapy in recurrent esophageal carcinoma after radical radiotherapy. Methods ： Total of 38 patients were given 3 - DCRT combined with chemotherapy. Resets： The orerall response rate was 89. 4% ,0）. 5% with CR,28.9% with PR ,SD 5.3% ,PD 5.3%, 1,2 year survival rates were 60.5% ,34 . 2% respectively. Conclusion： In patients with recurrent esophageal carcinoma after radical radiotherapy, 3 - DCRT combined with chemotherapy can improve local control, and increase survival rate.