宫颈癌调强放疗应用的剂量特点探讨

Dosimetric characteristic for cervical cancer patients receiving intensity modulated Radiation therapy

目的:分析10例宫颈癌调强放疗(IMRT)与箱式四野放疗各危及器官剂量差别和急性毒副反应,评价IMRT做为宫颈癌常规放疗的可行性。方法:选择2006年1月至2007年3月我科收治的10例宫颈癌根治性放疗患者,每位患者均同时作调强计划和箱氏四野计划,比较各危及器官的DVH曲线图。结果:两种方法处方剂量均较好的覆盖了靶区。在50Gy水平,IMRT中小肠、膀胱、直肠的体积分别减少了24.1%、38.1%、28.5%,患者副反应轻微,治疗过程中患者耐受性好。结论:IMRT在宫颈癌治疗中剂量分布优于箱式四野放疗。

Objective ：To analysis the impact difference between the IMRE and box fieldwork between organ dose and acute toxic reaction of 10 cases of cervical cancer. Methods ：Ten cervical cancer patients treated with radical radiotherapy were selected and do the planning of IMRT and box fieldwork for each of patient , the compare DVH cure to oberve the endanger organ. Results： The prescrption does of the two methods showed good coverage of target at 50 Gy,for IMRT,the volume of small intestine ,bladder,rectal decreased by 24.1% ,38.1% ,and 28.5%. Patients had less side effects , and well tolerated. Conclusion： IMRT has more advantages than four fields box of types in teletherapy with cervical carcinoma.