一株拮抗放线菌发酵液对试验性鸡大肠杆菌病的疗效试验

Efficacy of fermenting liquor of one antagonistic actinomycete on experimental colibacillosis in chicken

对一株具有抑菌效果的放线菌发酵液用于治疗鸡大肠杆菌病的疗效进行了研究。采用人工感染诱发鸡大肠杆菌病造模,分别以放线菌发酵液与氟苯尼考进行预防和治疗试验。结果显示,放线菌发酵液治疗组与氟苯尼考低剂量(5 mg/kg)组的大肠杆菌病治疗效果相当,差异不显著;放线菌发酵液预防组与感染对照组在死亡率、治愈率和增重方面差异显著。证实,试验所用的放线菌发酵液可用于治疗和预防人工诱发的O89血清型鸡大肠杆菌病。

Avian colibacillosis induced by the experimental infection method was treated and prevented using the fermenting liquor of antagonistic actinomycetes and florfenicol.The fermenting liquor treatment group（5mg/kg） had similar therapeutic effect to the low dose of florfenicol group,and the difference between the two groups was not significant（P0.05）.The difference between the fermenting liquor prevention group and the infection control group was significant in mortality,cure rate,and weight gain.The results showed that this fermenting liquor of actinomycete could treat and prevent O89 serotype avian colibacillosis induced by experimental infection.