中药人工周期法治疗女性迟发性痤疮疗效观察

Therapeutic Effect of Herbal-medicine Artificial Menstrual Cycle Therapy for Female Tardive Acne

目的:观察中药人工周期法治疗女性迟发性痤疮的临床疗效。方法:将105例女性迟发性痤疮患者随机分为治疗组57例与对照组48例。治疗组用中药人工周期法治疗,对照组用达英-35联合盐酸多西环素肠溶胶囊治疗。观察临床疗效、症状疗效及症状积分变化。结果:临床疗效治疗组总有效率为87.7%,愈显率为52.6%;对照组总有效率为66.7%,愈显率为35.4%。2组愈显率及总有效率比较,差异均有显著性意义(P<0.05)。症状疗效治疗组总有效率为91.2%,愈显率为56.1%;对照组总有效率为72.9%,愈显率为35.4%。2组愈显率及总有效率比较,差异均有显著性意义(P<0.05)。治疗组治疗2周积分即开始较治疗前显著下降,差异有非常显著性意义(P<0.01);对照组治疗4周积分开始显著下降,与治疗前比较,差异有非常显著性意义(P<0.01)。结论:中药人工周期法治疗女性迟发性痤疮疗效显著,值得临床推广应用。

Objective:To observe the therapeutic effect of herbal-medicine artificial menstrual cycle therapy for female tardive acne (FTA). Methods: One hundred and five FTA Patients were randomized into 2 groups:the treatment group (n=57) received herbal-medicine artificial menstrual cycle therapy,and the control group (n=48) received Diane-35 combined with doxycycline hydrochloride enteric capsules. Results:The total effective rate was 87.7% in the treatment group and 66.7% in the control group,and the remarkably effective rate was 52.6% in the treatment group and 35.4% in the control group,the difference being significant between the two groups (P < 0.05). The total effective rate on relieving symptoms was 91.2% in the treatment group and 72.9% in the control group,and the remarkably effective rate on relieving symptom was 56.1% in the treatment group and 35.4% in the control group,the difference being significant between the two groups (P < 0.05). The score of symptoms began to decrease in the treatment group after treatment for 2 weeks and in the control group after treatment for 4 weeks. Conclusion:Herbal-medicine artificial menstrual cycle therapy is effective for FTA.