期刊文献+

肺癌治疗前后呼出气冷凝液和血浆中CEA、ET-1水平研究 被引量:2

下载PDF
导出
摘要 目的研究肺癌治疗前后呼出气冷凝液和血浆中CEA、ET-1水平变化在肺癌诊治中的临床意义。方法采用放射免疫分析法和双抗体夹心生物素-亲和素酶联免疫吸附方法,分别在治疗前、治疗后2月、治疗后4月和治疗后6月对36例肺癌患者进行血液和EBC中CEA、ET-1水平的检测。结果①肺癌患者治疗前血清和EBC中CEA水平为42.37±27.52 ng/L和27.31±13.21 ng/L,与治疗后2月、治疗后4月和治疗后6月比较,差异有显著意义(P<0.05)。②肺癌患者治疗前血清和EBC中ET-1水平为125.78±48.28 ng/L和20.52±11.18 ng/L,与治疗后2月、治疗后4月和治疗后6月比较,差异有显著意义(P<0.05)。结论EBC中CEA、ET-1检测对肺癌的诊断有一定意义,在病情监测、评价治疗效果和预后等方面也有一定的作用。
作者 马航
出处 《临床肺科杂志》 2009年第12期1682-1683,共2页 Journal of Clinical Pulmonary Medicine
  • 相关文献

参考文献6

  • 1Tas F,Aydiner A,Topuz E, et al. Utility of the seBlm tumor mark- ers : CYFRA 21.1, carcinoembryonic antigen ( CEA ), and squamous cell carcinoma antigen ( SCC ) in squamous cell lung carcer. J Exp Clin Cancer Res ,2000,19 (4) :477 - 481.
  • 2张春燕,王玲珑,屠丽萍,余月华,俞月芳.应用IRMA对肺癌病人血清及呼出气冷凝液CEA水平的观察[J].放射免疫学杂志,2004,17(2):123-124. 被引量:7
  • 3Carpagnano GE, Foschino-Barbaro MP, Resta O, et al. Endothelin-1 is increased in the breath condensate of patients with non- small-cell lung cancer. Oncology, 2004,66 : 180 - 184.
  • 4Carpagnano GE, Foschino-Barbaro MP, Resta O, et al. Endothelin-I Is Increased in the Breath Condensate of Patients with Non-Small- Cell-Lung-Cancer. Oncology ,2004,66 : 180 - 184.
  • 5Boldrini L, Gisfredi S, Ursino S, et al. Expression of endothelin-I is related to poor prognosis in non-small cell lung carcinoma. Eur J Cancer,2005,41 ( 18 ) :2828 - 2835,.
  • 6Barlesi F, Gimenez C, Tone JP, et al. Prognastic value of combination of Cyfra 21-1. CEA and NSE in patients with advanced non- small cell lung cancer. Respir Med,2004,98:357 - 62.

二级参考文献1

  • 1潘中允.临床核医学[M].北京:原子能出版社,1999.123-124.

共引文献6

同被引文献31

  • 1韩志刚,单利,黄艳春,曲朝英.肿瘤标志物联合检测晚期肺癌的临床意义[J].新疆医科大学学报,2005,28(3):244-246. 被引量:4
  • 2Gessner C, Kuhn H, Toepfer K, et al. Detection of p53 gene muta- tions in exhaled breath condensate of non-small lung. Cancer 2004, 43:215 - 222.
  • 3Carpagnano GE, Foschino Barbam MP, Mule G, et al. 3p micrnsat-ellite alterations in exhaled breath condensate from patients with non-small cell lung cancer[ J]. Am J Respir Crit Care Med,2005, 172:738 - 744.
  • 4Carpagnano GE, Palladian GP, Gramiccioni C, et al. Exhaled ER- CC-1 and ERCC-2 micro satellite alterations in NSCLC patients[ J]. Lung Cancer,2010,68:305 - 307.
  • 5Carpagnano GE,Fosehino Barbaro MP, Resta O,et al. Endothelin-1 is increased in breath condensate of patients with non-small cell lung cancer [ J ]. Oncology ,2004,66 : 180 - 184.
  • 6Carpagnano GE, Spanevelio A, Curci C, et al. IL-2, TNF-alpha, and leptin:local versus systemic concentration in NSCLC patients [ J ]. Oncol Res,2007 ,16 :375 - 381.
  • 7Dalavefis E, Kerenidi T, Katsabeki Katsafli A, et al . VEGF, TNF-a and 8-isoproatane levels in exhaled breath condensate and serum of patients with lung cancer[ J]. Lung Cancer. 2009,64:219 - 225.
  • 8Clumli P,Tran V, Lewis C,et al. Elevated levels of oxidative stress markers in exhaled breath condensate[ J]. J Thorae Oncol,2009,4: 172 - 178.
  • 9Phillips M, Ahorki N, Austin JH, et al. Prediction of lung cancer u- sing volatile biomarkers in breath [ J ]. Cancer Biomarkers, 2007,3: 95 - 109.
  • 10Phillips M, H errera J , Cataneo RN, et al. Variation in volatile or- ganic compounds in the breath of normal humans. J Chromatogr[ J ]. B V Biomed Sei Appl, 1999,729(1/2) : 75 -88.

引证文献2

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部