摘要
目的:分析我院药品不良反应(ADR)发生的特点与一般规律,促进临床合理用药。方法:对我院354份ADR报告,按患者的性别、年龄、引起ADR的药品种类、给药途径、涉及器官或系统以及临床表现等进行统计分析。结果:354例ADR中,主要与静脉给药方式、患者年龄较大、抗感染药使用以及中药注射剂的质量有关。静脉滴注较其它给药途径更易发生ADR,ADR最常见表现为皮肤及其附件损害。结论:应加强ADR监测意识,完善相关报告分析制度,促进临床合理用药。
OBJECTIVE： To analyze the characteristics and the general pattern of adverse drug reactions （ADRs） occurred in our hospital in order to promote clinical rational use of drugs. METHODS ： A total of 354 ADR cases reported in our hospital were analyzed statistically in respect of patients＇ age and sex, drug categories, route of administration, organs or systems involved and clinical manifestations etc. RESULTS： Of the 354 ADR cases, the ADRs were mainly associated with intravenous administration, older age, use of antiinfective drugs and the quality of traditional Chinese medicinal injections. Intravenous drip infusion was more likely to induce ADRs than the other routes of administration. The ADRs were mainly manifested as lesions of skin and its appendages. CONCLUSION： It is advisable to strength our consciousness on ADR monitoring and improve the related ADR reporting system to promote clinical rational use of drugs.
出处
《中国医院用药评价与分析》
2009年第11期866-868,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
监测
统计分析
Adverse drug reaction （ADR）
Monitoring
Statistical analysis
