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坎地沙坦酯对高血压合并2型糖尿病患者的影响 被引量:2

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摘要 高血压合并糖尿病患者发生心血管并发症的危险性比单纯高血压患者高3~4倍,且预后差,病死率高。这种现象可能与胰岛素抵抗和血管紧张素Ⅱ过度激活有关。坎地沙坦酯(candesartan cilexetil)是一种具有高度选择性的血管紧张素Ⅱ受体(AT1型)拮抗剂,生物利用度高、降血压作用持久、不良反应发生率低。该药可安全有效地治疗轻中度高血压病。本研究旨在观察其对高血压合并2型糖尿病患者糖代谢、胰岛素敏感性及血压的影啊隋况。
出处 《中国药物与临床》 CAS 2009年第11期1100-1102,共3页 Chinese Remedies & Clinics
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