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伊马替尼作为老年性Ph阳性急性淋巴细胞白血病一线治疗与化疗的对照研究 被引量：4

Imatinib Compared with Chemotherapy as Front-Line Treatment of Elderly Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ALL)
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摘要 1文献来源 Ottmann OG, Wassmann B, Pfeifer H, et al. Imatinib compared with chemotherapy as front-line treatment of elderly patients with Philadelphia chromosome-positive acute lymphoblastic leukemia （Ph＋ALL） [J]. Cancer, 2007,109（10）：2068-2076.
作者 吴德沛 钟立业
机构地区 苏州大学第一附属医院血液科 广东省人民医院肿瘤中心血液科
出处 《循证医学》 CSCD 2009年第5期270-273,共4页 The Journal of Evidence-Based Medicine
关键词 急性淋巴细胞白血病 费城染色体 BCR—ABL 微小残留病灶 随机对照试验 acute lymphoblastic leukemia Philadelphia chromosome BCR-ABL minimal residual disease randomized controlled trial
分类号 R733.71 [医药卫生—肿瘤]
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参考文献6

  • 1Ottmann OG, Druker BJ, Sawyers CL, et al. A phase 2 study of Imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias [J]. Blood, 2002, 100(6) : 1965-1971.
  • 2Druker BJ, Sawyers CL, Kantarjian H, et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic lekemia with the Philadelphia chromosome [J]. N Engl J Med, 2004,344(14) : 1038-1042.
  • 3Wassmann B, Pfeifer H, Scheuring U J, et al. Early prediction of response in patients with relapsed or refractory Philadelphia chromosome positive acute lymphoblastie leukemia (Ph+ALL) treated with imatinib mesylate (Glivec) [J]. Blood, 2004,103 (4) : 1495-1498.
  • 4Hoelzer D, Gokbuget N. New approaches to acute lymphoblastic leukemia in adults: Where do we go? [J]. Semin Oncol, 2000,27(5) :540-559.
  • 5Radich JP. Philadelphia chromosome-positive acute lymphocytic leukemia [J]. Hematol Oncol Clin North Am, 2001,15 (1): 21-36.
  • 6Delannoy A, Delabesse E, Lheritier V, et al. Imatinib and methylprednisolone alternated with chemotherapy improve the outcome of elderly patients with Philadelphia-positive acute lymphoblastic leukemia: Results of the GRAALL AFR09 study [J]. Leukemia, 2006,20(9) : 1526-1532.

同被引文献30

  • 1W assmann B.Alternating versus concH/Tent schedules of imatinib and chemotherapy as front-line therapy for Philadelphia-positive acute lymphoblastic leukemia(Ph+ALL).Blood,2006,108(5):1469-1477.
  • 2秘营昌.成人急性淋巴细胞白血病的治疗[J].国际输血及血液学杂志,2007,30(5):385-390. 被引量：6
  • 3Yanada M, Takeuehi J,Sugiura I,et al. High complete re- mission rate and premising outcome by combination of I- matinib and chemotherapy for newly diagnosed BCR- ABL-Positive acute lymphoblastic leuke-mia : a phase 11 study by the Japan adult leukemia study group[J]. Jourual of Clinical Oncology, 2006,24 (3) : 460-466.
  • 4Lee HJ,Thompson JE,Wang ES,et al. Philadelphia chro- mosome-positive acute lymphoblastic leukemia[J]. Cancer, 2011,117 (8) : 1583-1594.
  • 5Wassmann B ,Pfeifer H,Scheuring UJ,et al. Early prediction of response in patients with relapsed or refractory Philadel- phia chromosome positive acute lymphoblastie leukemia (Ph^+ALL) treated with imatinib mesylate (Glivec)[J]. Blood,2004,103 (4) : 1495-1498.
  • 6Hernandez JM, Granada I, Sole F, et al. From convention- al cytogenetics to microarrays. Fifty years of Philadelphia chromosome[J]. Mad Clin (Sarc), 2011,137 (5) : 221-229.
  • 7Druker BJ,Sawyers CL,Kantarjian H,et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lym- phoblastic lekemia with the Philadelphia chromosome[J]. N Engl J Med,2004,344(14) : 1038-1042.
  • 8Wassmann B, Pfeifer H, Goekbuget N, et al. Alternating versus concurrent schedules of imatinib and chemotherapy as front-line therapy for Philadelphia-positive acute lym- phoblastic leukemia(Ph^+ ALL)[J]. Blood,2006,108 (5) : 1469- 1477.
  • 9Druker B J, Guilhot F, O'Brien SG, et al. Five-year fol- low-up of patients receiving imatinib for chronic myeloid leukemia[J]. N Engl J Med, 2006,355 (23) : 2408 -2417.
  • 10Gorre ME,Mohammed M, Ell wood K, et al. Clinical re- sistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplifieation[J]. Science,2001,293 (5531) : 876-880.

引证文献4

二级引证文献15

循证医学
2009年 第5期

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