三联空压泵雾化吸入治疗喘息型肺炎的疗效观察

Efficacy of triad nebulization in patients with epidemic bronchiolitis

目的探讨三联空气压缩泵雾化吸入治疗喘息型肺炎的疗效。方法将我院100例住院的喘息型肺炎患儿按住院号单双分为2组:治疗组(n=50)和对照组(n=50)。两组综合治疗相同,在此基础上治疗组给予异丙托溴胺、布地萘德、沙丁胺醇三联空气压缩泵雾化吸入,对照组为常规的静脉用氢化可的松。观察两组咳嗽、喘息、哮鸣音及湿啰音消失的时间、住院天数及药物不良反应。结果治疗组咳嗽、喘息、肺部哮鸣音、湿啰音持续时间均明显短于对照组,住院天数也短于对照组(P<0.01),且治疗组未发现不良反应。结论三联雾化吸入治疗喘息型肺炎疗效更佳,短期使用无不良反应。

Objective To explore the effect of triad nebulization on the epidemic bronchiolitis. Methods One hundred children with epidemic bronchiolitis were randomly assigned into two groups：treatment group（ n = 50）and control group （n = 50）. Based on the general therapy, the patients in treatment group inhaled budesonide, salbufamol and ipratropium bromide, while the children in control group were injected intravenously with hydrocortisone. The hospitalization days, duration of cough, pant, wheezes, pulmonary crackles and side effects of the drugs were recorded. Results The average hospitalization time, duration of cough, pant, wheezes, pulmonary crackles in treatment group were shorter than in control group（ P 〈 0. 01 ）. No adverse effects were found in treatment group. Conclusion Triad nebulization may be an effective therapy for epidemic bronchiolitis.