过程产物硫化氢还原硝基苯替代苯胺合成2-巯基苯并噻唑的初步探索

Synthesis of 2-Mercaptobenzothiazole Using Nitrobenzene and H2S as Starting Materials

尝试用苯胺法合成橡胶促进剂2-巯基苯并噻唑的副产物硫化氢还原硝基苯得到苯胺,产物苯胺不经分离直接与二硫化碳、硫磺合成2-巯基苯并噻唑,硫化氢在整个体系中循环利用,还原产物单质硫又作为生产2-巯基苯并噻唑的原料。实验还原反应条件为,温度80～100℃,反应时间3～4 h,在一定压力下,硫化氢可以将硝基苯部分还原成苯胺,经检测分析知苯胺的最高收率可达6.619%。在还原后产物中直接加入溶硫液制得2-巯基苯并噻唑。该法提供了一种新的低成本、环保的2-巯基苯并噻唑的生产方法。

H2S which was the by-product from 2-mercaptobenzothiazole synthesis process reacted with nitrobenzene to prepare aniline and the obtained aniline was directly used to synthesize 2-mercaptobenzothiazole. The sulfur obtained from reduction process was used as material for synthesizing 2-mercaptobenzothiazole. That is to say the byproducts H2 S and sulfur could be utilized circularly. Under the conditions of 80～ 100 ℃, certain pressure and 3～4 h, the yield of aniline could reach 6. 619%. The feasibility of experiment was done by adding sulfur dissolved in carbon disulfide could be directly added to the reduction mixture to prepare 2-mercaptobenzothiazole. A new clean synthesis method of 2-mercaptobenzothiazole with lower cost is explored.