注意缺陷多动障碍儿童生存质量的评价

Quality of Life of Children with Attention Deficit Hyperactivity Disorders

目的评估注意缺陷多动障碍(ADHD)儿童的生存质量。方法采用横断面病例对照研究设计。病例组为73例ADHD儿童(ADHD组),正常对照组(对照组)为与ADHD组性别、年龄匹配的98例正常儿童。使用儿科生存质量测定量表(pediatric quality of life inventoryTM version 4.0,PedsQLTM 4.0)中文版普适性核心量表、Conners父母问卷对儿童及其父母评估。结果调查的171个家庭中169个家庭完成问卷,应答率98.8%。ADHD儿童PedsQLTM 4.0中文版儿童评分总分(72.7±13.0)比对照组(83.7±12.0)低(t=-49.3,P=0.000),父母报告评分总分(70.0±12.4)比对照组(82.4±11.2)低(t=-57.7,P=0.000)。ADHD儿童心理领域分(儿童评分68.6±14.5,父母报告评分64.9±15.4)比生理领域分(儿童评分81.2±14.0,父母报告评分81.7±15.6)低(t=3.79、6.88,P=0.000)。ADHD儿童Conners父母问卷总分(44.54±17.89)高于对照组(16.09±9.23)(t=100.08,P=0.000)。ADHD儿童PedsQLTM 4.0中文版角色功能儿童自评评分与Conners父母问卷学习问题、多动指数、总分呈负相关(r=-0.650、-0.630、-0.599,P=0.000)。结论ADHD儿童生存质量较正常儿童差,品行、学习、冲动控制等问题与之有关。

Objective To assess the quality of life of children with attention deficit hyperactivity disorders（ADHD）.Methods The PedsQL TM 4.0 generic core scales（Chinese Version） were administered to 73 ADHD children and 98 gender and age-matched healthy children.The parents of the children completed the Conners Parent Symptom Questionnaire.Results A total of 169 out of 171 recruited families completed the questionnaires,with a response rate of 98.8%.The ADHD children had significantly lower scores（72.7±13.0） of PedsQL TM 4.0 than that of the healthy children（83.7±12.0,t =-49.3,P =0.000）.The Parent Proxy-Report total score of the ADHD children（70.0±12.4） was also lower than the normal controls（82.4±11.2,t =-57.7,P =0.000）.The psychosocial health functioning of ADHD children（Children Self-Report 68.6±14.5,Parent Proxy-Report 64.9±15.4） was consistently poorer than the Physical Functioning（Children Self-Report 81.2±14.0,Parent Proxy-Report 81.7±15.6）（P =0.000）.The ADHD children had significantly higher scores in Conners Parent Symptom Questionnaire（44.54±17.89） than the normal controls（16.09±9.23,t =100.08,P =0.000）.The PedsQL TM 4.0 scores were negatively correlated with school functioning scores,learning problems,hyperactivity index and the total scores of Conners Parent Symptom Questionnaire（r =-0.650,-0.630,and-0.599 respectively,P =0.000）.Conclusion ADHD children suffer from poor quality of life and learning difficulties.