应用ROC曲线对比颈动脉超声标识与传统危险因素预测冠心病价值

Compare the Predicting Value of Carotid Artery Ultrasound and Traditional Risk Factors by Application of ROC Curve

目的应用ROC曲线对比颈动脉超声标识与传统危险因素预测冠心病价值。方法252例患者行冠状动脉造影同时行颈动脉超声检测,并将颈动脉内膜-中层厚度(IMT)、冠心病危险因素(高血压病、高血脂、糖尿病)作为数据源,描绘ROC曲线及计算ROC曲线下面积。结果218例患者冠状动脉造影阳性,颈动脉超声标识预测冠心病ROC曲线下面积为0.844、血脂异常为0.791、高血压病为0.719、糖尿病为0.651(P均<0.05～0.01)。结论颈动脉超声标识预测冠心病价值明显高于传统危险因素,可作为冠心病确诊的重要参考条件。

Objective To compare the predicting value of the carotid intima - media thickness （IMT） and traditional risk factors for the diagnosis of coronary heart disease. Methods 126 hospitalized patients who had the history of paroxysm of chest pain that might be caused by the coronary artery disease were enrolled. The mean ages of the patients were 56 ± 6.5 years, and 87 of the patients were male. They all had undergone the ultrasonography to measure carotid artery and coronary angiography （CAG） by the means of Jerkin＇ s. Results 252 patients got the definite diagnosis of coronary heart disease by the CAG. The area under ROC curve was 0. 844（P 〈 0.01 ）. Conclusion The increasing thickness in carotid intima - media can be used as independent predictors risk factors for coronary heart disease.