肺癌CT伪彩成像红色色彩程度与MVD的关系

The Relationship between the Extent of Red Color on Pseudocolor CT Image and MVD in Lung Carcinoma

目的:探讨肺癌16层螺旋CT伪彩成像肿瘤红色色彩程度与其微血管密度(MVD)关系。材料和方法:25例肺癌行16层螺旋CT增强扫描及肿瘤病灶VR伪彩成像,对每个病灶进行免疫组化MVD计数检测。用肿瘤VR伪彩成像红色色彩程度代表肿瘤增强状况,分析肺癌病灶VR伪彩成像红色色彩程度与肿瘤MVD计数关系。结果:重度红色色彩肺癌5例、中度红色色彩肺癌8例、轻度红色色彩肺癌9例和无红色色彩肺癌3例。13例VR伪彩成像重和中度红色色彩肺癌增强增加CT值为26.32±9.17Hu,肿瘤MVD计数为57±6.43。12例VR伪彩成像轻及无红色色彩肺癌增强增加CT值为10.87±4.257Hu,肿瘤MVD计数为19±5.29。重、中度色彩组与轻或无色彩组肺癌MVD计数差异显著。结论:肺癌CT伪彩成像红色色彩程度与其肿瘤MVD有一定相关性,可初步反映其MVD状况。

Purpose： To discuss the relationship between the extent of red pseudocolor of pseudocolor CT image and MVD in lung carcinoma. Materials and Methods： The CT angiography was performed by using 16-slices spiral CT in 25 cases with pulmonary carcinoma,proved by pathology. Pseudocolor VR of tumor lesions of pulmonary carcinoma was performed. The immunohistochemical test of MVD of tumor lesion of pulmonary carcinoma was performed in 25 cases. The relation between the extent of red color on pseudo color VR and MVD of tumor lesion of pulmonary carcinoma were analyzed. Results： The extents of red pseudocolor of tumor lesion on VR pseudocolor Imaging were divided to four types ： heavy （ n = 5 ）, moderate （ n = 8 ）, light （ n = 9 ）, no color（ n = 3 ）. The add CT values of tumor lesion after enhanced CT were 26.32 4-9.17Hu in 13 cases with heavy or moderate group, 10.87±4. 257Hu in 12 cases with light or no red color group. The numbers of MVD of tumor lesion of pulmonary carcinoma were 57±6.43 in 13 cases with heavy or moderate group , 19±5.29 in 12 cases with light or no red color group. The numbers of MVD of pulmonary carcinoma had statistical significant between heavy or moderate group and light or no red color group. Conclusion： It has a significantly direct correlation between the extent of red pseudocolor of tumor lesion on pseudocolor image and MVD of tumor lesion in pulmonary carcinoma.