胸腹水TP、ADA、LDH、CA125四项指标联合检测的临床意义

The clinic significance of the four joint examinations TP,ADA,LDH and CA125 for the pleural fluid and ascites patient

目的探讨胸腹水总蛋白(TP)、腺苷脱氢酶(ADA)、乳酸脱氢酶(LDH)、糖基抗原125(CA125)四项指标联合检测在良、恶性胸腹水中的临床鉴别诊断意义。方法回顾性分析我院2007～2008年住院诊断有胸腹水的患者,分成良性肿瘤组和恶性肿瘤组两组,分析两组患者胸腹水中TP、ADA、LDH、CA125的检测结果,数据采用方差分析法进行统计分析。结果恶性组患者胸腹水标本中TP、LDH、CA125值较良性组明显升高(P<0.05),ADA结果良性组高于恶性组(P<0.05)。结论联合检测TP、ADA、LDH、CA125对胸腹水性质的鉴别诊断有重要临床参考价值。

Objective To discuss the clinic diagnostic significance of the four joint examinations TP, ADA,LDH and CA125 for the benign and malignant pleural fluid and ascites patients. Methods Anylyzed retrospectively the inpatients who had been diagnosed as pleural fluid and ascites during 2007-2008 by dividing them into benign group and malignant group. Anylyzed the outcome of the TP,ADA,LDH,CA125 in the two groups,the data was disposed with analysis of variance. Results The numerical value of TP,LDH,CA125 in the samples from the malignant group rose obviously higher than those from the benign group（P〈0.05 ）;The outcome of ADA from benign group was higher than that from the malignant group （P〈0.05）. Conclusion The joint examination of TP,ADA,LDH,CA125 has important clinic referenced value to diagnose the character of the pleural fluid and ascites.