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95例急性心肌梗死患者血清肌钙蛋白测定分析与探讨 被引量:5

The analysis and approach of detecting the serum troponin in the patients with acute myocardial infarction
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摘要 目的探讨急性心肌梗死(AMI)患者血清肌钙蛋白测定分析与价值。方法95例AMI患者,同时设健康对照组50例,观察AMI患者及健康体检者血清肌钙蛋白T(cTnT)和肌酸激酶同工酶(CK-MB)变化。结果AMI组与对照组相比,cTnT和CK-MB结果差异有统计学意义(P<0.05)。且cTnT和CK-MB在各时间点阳性率不同,cTnT血清活性升高快,在AMI发作后4h其阳性率比较差异有统计学意义(P<0.05)。结论cTnT可有效监测病情的发展、治疗及预后,有助于判断溶栓的疗效,并且能提示患者的预后,可以在临床推广应用。 Objective To investigate the determination and value of serum troponin in the patients with acute myocardial infarction. Methods cTnT and CK-MB were detected in 89 cases of acute myocardial infarction patients and 52 normal control persons. Results The cTnT and CK-MB of AMI group and normal control group had highly significant difference(P〈0.05). The masculine rate of cTnT and CK-MB at each time were different. The activity of cTnT increased quickly, and masculine rate had highly significant difference after 4h of AMI attack (P〈0.05). Conclusion cT-nT had the effects of monitoring the development of pathogenetic condition, treatment and prognosis, and it can also help to judge the effects of thrombolysis and deserves extended application in clinic.
出处 《检验医学与临床》 CAS 2009年第22期1901-1901,1903,共2页 Laboratory Medicine and Clinic
关键词 急性心肌梗死 肌钙蛋白T 肌酸激酶同工酶 acute myocardial infarction cTnT CK-MB
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