急性附睾炎发病与慢性前列腺炎相关性研究

Research of the correlation between the incidence of acute epididymitis and chronic prostatitis Correlative analysis between acute epididymitis and chronic prostatitis

目的探讨急性附睾炎发病与慢性前列腺炎（CP）的相关性。方法回顾性分析1998年1月至2008年1月163例急性附睾炎患者临床资料，根据阴囊有无红肿热痛、发烧、检查结果及美国国立卫生研究院慢性前列腺炎症状指数（NIH-CPSD评分作为诊断急性附睾炎和慢性前列腺炎的标准。常规抗炎及对症治疗。比较CP治疗前后NIH—CPSI评分并进行统计学分析。结果163例患者皆被诊断为急性附睾炎。其中159例（97．55％）被诊断为合并慢性前列腺炎者，前列腺液检查显示：WBC10-满视野／高倍镜视野（He）（其中WBC满视野／HP116例，占71．6％），WBC正常者4例（2．45％），卵磷脂小体（＋～＋＋）／HP148例（90．79％），卵磷脂小体正常者15例（9．20％）。25例有冶游史患者发现衣原体感染者6例（3．78％）。163例急性附睾炎患者经治疗后162例痊愈，1例治疗无效后行附睾切除术。Spearman秩相关分析相关系数rs=0．9998，P〈0．05，治疗后较治疗前NIH—CPSI评分明显下降[（47±14）分下降至（28±17）分]。结论附睾炎的发病与慢性前列腺炎有显著的相关性，亦即慢性前列腺炎是急性附睾炎发病的重要因素之一。

Objective To investigate the correlation between the incidence of acute epididymitis and chronic prostatitis. Methods Between January 1998 and January 2008, 163 cases were collected. Acute epididymitis, including age, symptoms, signs, history of dirty sex and urine, EPS routine examination, B-ultrasound, prostatic fluid bacterial culture and sensitivity test were analyzed. NIH chronic prostatitis symptom index （NIH-CPSI） was compared before and after treatment. Result One hundred and sixty three cases were treated with conventional treatment, 159 eases were diagnosed of prostatitis. 6 cases with a dirty sex-life history had chlamydial infection. After conventional treatment, 162 cases of epididymitis were cured. No scrotal palpation and swollen epididymis were observed. One hundred and fifty-nine cases receiving EPS routine examination were back to normal. After treatment, NIH-CPSI score decreased significantly. Conclusion The incidence of epididymitis and chronic prostatitis is significant correlation, and chronic prostatitis is an important factor in the pathogenesis of acute epididymitis.