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延迟PCI对急性心肌梗死患者血浆脑钠肽N末端前体的影响

The effect of delayed PCI on NT-proBN in patients with acute myocardial infarction
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摘要 目的:探讨延迟经皮冠状动脉介入(PCI)对急性心肌梗死(AMI)患者心功能的影响。方法:选择住院治疗的AMI患者97例,根据是否行延迟PCI术分为两组,两组患者均于入院即刻、心梗后7天、6个月左右检测血浆脑钠肽N末端前体(NT-proBNP)水平的变化;分别于AMI后2周、心梗后6个月左右做心脏超声检查,测定左室射血分数(LVEF),左室舒张末期容积(EDV)。对比PCI组和非PCI组两组患者心脏超声和NT-proBNP的动态变化。结果:6个月后PCI组的NT-proBNP低于非PCI组(P<0.01);PCI组的LVEF值明显高于非PCI组(P<0.05),非PCI组EDV明显大于PCI组(P<0.05)。结论:延迟PCI能改善AMI患者的心功能。 Objective:To evaluate the efficacy of delayed PCI on heart function in patients with acute myocardial infarction. Methods:97 patients with AMI were divided into the treatment group and the control group . Based on PCI -group and non-PCI group , the plasma BNP levels were measured in these patients immediately and 7 days and 6 months after AMI. Left ventricular volume indees, ejection fraction and left ventricular end diastolic end volume indexes were measured in 2 weeks and 6 months in each group after AMI. Results:6 months after AMI,BNP in the PCI group was singnificantly lower than that in the non-PCI group, left ventricular end diastolic volume in non-PCI group was singnificantly larger than in the PCI group. Conclusion:Delayed PCI for infarctrelated artery would inhibit ventricular enlargement benefiting to the heart function.
出处 《交通医学》 2009年第5期473-475,共3页 Medical Journal of Communications
关键词 延迟经皮冠状动脉介入 血浆脑钠肽N末端前体 心功能 delayed PCI N-terminal pro-brain natriuretic peptide BNP(NT-proBNP) heart function.
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