基底动脉尖综合征36例临床分析

Clinical analysis on 36 patients with top of basilar syndrome

目的探讨基底动脉尖综合征(TOBS)的病因、临床表现、影像学特点及预后。方法回顾性分析36例TOBS患者的临床资料。结果TOBS的主要病因为脑栓塞及脑血栓形成,临床以意识障碍、眼球运动障碍、瞳孔改变为主要表现,磁共振成像发现中脑、丘脑、小脑、枕叶及颞叶内侧等多个部位存在梗死灶,脑疝及并发症为主要死亡原因。结论TOBS临床表现多样,及早诊断、积极治疗对预后至关重要。

Objective To investigate the etiological factors,clinical manifestations,imaging findings and prognosis of patients with top of basilar syndrome（TOBS）.Methods Clinical data of 36 patients with TOBS were retrospectively reviewed and analyzed.Results Cerebral thrombosis and cerebral embolism were the major causes of TOBS.Its clinical manifestations included conscious disturbances,ocular movement disorder and pupillary change.MRI showed local infarction in midbrain,thalamus,cerebellum,occipital lobus,temporal inner surface.Herniation and complications were main causes responsible for its death.Conclusion Clinical manifestations of TOBS are diverse.Early diagnosis and active treatment are very important for its prognosis.