酶联检测CA_(125)在妇科的应用

Use of CA 125 Level Detecting by ELISA in Gynecologic Clinic

采用酶联法（ＥＬＩＳＡ）检测了２２９例妇科患者的血清上皮性卵巢癌抗原（ＣＡ１２５），并进行分析。结果：１卵巢癌患者血清ＣＡ１２５明显高于良性病例，两者阳性率分别为８１２５％和８９％，有极显著性差异（Ｐ＜０００１），其中浆液性癌阳性率明显高于粘液性癌，分别为９３７％和７０％；２内膜异位症ＣＡ１２５水平亦升高，阳性率为５２６％。结论：ＥＬＩＳＡ检测血清ＣＡ１２５与传统的放免法（ＲＩＡ）相比，具有同等的诊断价值，在应用上具有便捷，药盒保存时间长，无污染等优点。

To investigate clinical signifcance of detecting the serum CA 125 in Engyme-Linked immuno sorbent assay (ELISA). Examine serum CA 125 contens of 229 gynaecopathia patients in ELISA and clinical analysis of them.1 The serum CA 125 of ovarion caners were obviously higher than those benign diseases (P<0 001). The positive ratio of ovarion cancers is 81 25% and that of the benige clisenses is 8.9%. In Which the positive ratio of seveus cancers in obviously higher than that of mucinous cancers (97.3%,70%).2 The CA 125 level of endometriosis increases to positive ratio is 52.6%. CA 125 is a senstitive sign of epithelial cancer. Compared with traclional RIA, ELISA examing serum CA 125 has the same chiagnostic value, additional, it has some advantages: giuck and convenient opertion, long-time coseration in a medicine-box,no polution, reguire of test condition is not high rank, so that it is suitable to be applied in basic unit hospital and general surrey, it is a method worth popularizing.