期刊文献+

细胞自噬在病原体感染过程中的作用研究进展 被引量:9

Research progress of the role of autophagy in infectious diseases
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摘要 细胞自噬是一种通过降解蛋白质和细胞器维持细胞内平衡的细胞机制。细胞自噬具有很多重要的生理功能,包括清除病原体的感染。但是由于细胞自噬在进化过程中具有高度的保守性,某些病原体通过进化,具有逃避细胞自噬的能力,甚至利用细胞自噬为病原体复制和发育提供有利条件。本文综述了细胞自噬与病原体相互作用的研究进展。 Autophagy regulates the intracellular homeostatic mechanism that mediates the degradation of proteins and organelles. Autophagy plays a number of roles in various cellular physiological functions, involving intracellular pathogens clearance. Since autophagy is highly conserved, some pathogens have evolved to evade autophagy utilizing different strategies. This article mainly reviews the function of autophagy in pathogens.
出处 《军事医学科学院院刊》 CSCD 北大核心 2009年第5期469-472,共4页 Bulletin of the Academy of Military Medical Sciences
关键词 细胞自噬 病原体 细胞自噬相关基因 autophagy pathogen autophagy related gene
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参考文献29

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同被引文献101

  • 1林芳,顾振纶,秦正红.自噬及其在细胞代谢和疾病中的作用[J].生物化学与生物物理进展,2005,32(4):298-303. 被引量:21
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