摘要
病原菌给人类带来的危害极大。快速、准确、灵敏、特异地对病原体作出诊断,是有效预防感染性疾病发生和控制其迅速传播的前提和关键。基因芯片技术以其具有高通量、快速灵敏、样品用量少等显著特点在病原菌检测中发挥着越来越重要的作用。本文综述了基因芯片技术在检测致病菌方面的应用、存在的问题及发展前景。
Pathogenic bacteria cause huge damage to human beings. To find a rapid, specific, sensitive method for detection of pathogenic bacteria is a very important prerequisite for prevention and control of infectious diseases. DNA microarray which is a high-throughput, rapid method and needs few samples has been considered as a potential approach to the detection of pathogenic bacteria. In this review the application, unsolved problems and prospect of the technology in pathogenic bacteria detection are introduced.
出处
《军事医学科学院院刊》
CSCD
北大核心
2009年第5期479-482,共4页
Bulletin of the Academy of Military Medical Sciences
关键词
芯片分析技术
细菌
基因
聚合酶链反应
microarray analytical procedures
bacteria
genes
polymerase chain reaction