中药饮片丹参的质量考察

Examine the quality of Chinese medicine Danshen Pieces

目的:考察流通市场中药饮片丹参的质量。方法:通过薄层色谱法、紫外分光光度法、高效液相色谱分析法考察丹参不同品种、不同制品饮片的质量。结果:丹参饮片不同品种、不同制品紫外吸收均在(204±2)nm波长处有最大吸收;薄层色谱分析全部样品在Rf值0.25处有橘黄色斑点,在Rf值0.80处有橘红色斑点,栽培丹参、白花丹参在Rf值0.91处各有橘黄色斑点;高效液相含量测定丹参样品⑥、⑦含丹参酮ⅡA>中国药典规定的0.20%,其他样品均<0.20%。丹酚酸B的含量均符合中国药典规定。结论:本方法可用于丹参、酒制丹参的质量控制;只有栽培丹参、白花丹参丹参酮ⅡA的含量符合中国药典项下规定,其他样品均不符合规定,其原因是栽培时间短(1年)所致。为了保证丹参的药品质量,栽培时间以2年以上为宜。

Objective：To investigate the distribution market pieces of chinese medicine Danshen quality. Methods：The thin-layer chromatography, UV spectrophotometry, high performance liquid chromatography Salvia examine different varieties of quality products Pieces. Results： Salvia Pieces of different varieties, different products were UV absorption at （204 ±2） nm wavelength of maximum absorption; thin-layer chromatography analysis of all samples in the Rf value of 0.25 with orange spots, in the Rfvalue of 0.80 has orange-red spots, cultivation Salvia, Salvia white flowers in the Rf value of 0.91 each orange spots; HPLC determination of ⑥,⑦ Danshen samples containing tanshinone Ⅱ A〉 Chinese Pharmacopoeia 0.20%, while other samples were less than 0.20%. Dan acid contents of B are in line with the provisions of the Chinese Pharmacopoeia. Conclusion：This method can be used Salvia, Salvia liquor system of quality control; only cultivation Salvia, Salvia white flowers in line with the content of tanshinone Ⅱ A Chinese Pharmacopoeia under the provisions of other samples do not meet requirements, the reason is the cultivation time is short （1 year ）-induced. In order to ensure the quality of medicines Salvia, planting time for 2 years and over.