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生长素结构与其活性关系的揭示 被引量：4

Elucidation of Relationship between Auxin Structure and Its Activity
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摘要 生长素结构与活性之间关系是长期以来悬而未决的一个难题。最近的研究证明,生长素分子像"胶水"一样将受体TIR1与效应蛋白Aux/IAA"粘合"后,形成SCFTIR1-生长素-Aux/IAA复合物,进而激活泛素连接酶3(SCFTIR1),起着促使Aux/IAA泛素化后的降解,转录因子ARFs得到活化后,启动一系列生长素响应基因的转录,于是植物表现出相应的生长发育状态。
作者 杨艳会 张清哲 陈军营 陈新建
机构地区 河南农业大学农学院
出处 《植物生理学通讯》 CSCD 北大核心 2009年第11期1119-1124,共6页 Plant Physiology Communications
基金 国家转基因植物研究与产业化专项基金(JY03-B-19-2) 河南省杰出人才创新基金(022100090)
关键词 生长素结构 受体 作用机理 分子胶
分类号 Q946 [生物学—植物学]
  • 相关文献

参考文献25

  • 1白华举,陈军营,刘林,陈新建.TIR1终于被确证为生长素受体[J].植物生理学通讯,2006,42(4):731-735. 被引量：11
  • 2Abel S, Nguyen MD, Theologis A (1995). The PS-IAA4/5-like family of early auxin-inducible mRNAs in Arabidopsis thaliana. J Mol Biol, 251:533-549.
  • 3Bertosa B, Kojic-Prodic B, Wade RC, Ramek M, Piperaki S, Tsantili-Kakoulidou A, Tomic S (2003). A new approach to predict the biological activity of molecules based on similarity of their interaction fields and the logP and logD values: application to auxins. J Chem Inf Comput Sci, 43:1532-1541.
  • 4Dharmasiri N, Dharmasiri S, Estelle M (2005). The F-box protein TIR1 is an auxin receptor. Nature, 435:441-445.
  • 5Edgerton MD, Tropsha A, Jones AM (1994). Modeling the auxinbinding site of auxin-binding protein-1 of maize. Phytochemistry, 35:1111 -1123.
  • 6Gray WM, Kepinski S, Rouse D, Leyser O, Estelle M (2001). Auxin regulates SCF^TIRI-dependent degradation of Aux/IAA proteins. Nature, 414:271-276.
  • 7Gtickman MH, Ciechanover A (2002). The ubiquitin-proteasome protelytic pathway: destruction for the sake of construction. Physiol Rev, 82:373-428.
  • 8Hansch C, Muir RM (1950). The ortho effect in plant growthregulators. Plant Physiol, 25:389-393.
  • 9Hayashi KI, Tan X, Zheng N, Hatate T, Kimura Y, Kepinski S, Nozaki H (2008). Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and singnaling. Proc Natl Acad Sci USA, 105:5632-5637.
  • 10Irvine RF, Schell MJ (2001). Back in the water: the return of the inositol phosphates. Nature Rev Mol Cell Biol, 2:327-338.

二级参考文献25

  • 1Woodward AW,Bartel B(2005).A receptor for auxin.Plant Cell,17:2425～2429
  • 2Yang X(2004).The IAA1 protein is encoded by AXR5 and is a substrate of SCFTIR1.Plant J,40:772～782
  • 3Abel S,Nguyen MD,Theologis A(1995).The PS-IAA4/5-like family of early auxin-inducible mRNAs in Arabidopsis thaliana.J Mol Biol,251:533～549
  • 4Batt S,Wilkens MB,Venis MA(1976).Auxin binding to corn coleoptile membranes:kinetics and specificity.Planta,130:7～13
  • 5Chen JG,Ullah H,Young JC,Sussman MR,Jones AM(2001).ABP1 is required for organized cell elongation and division in Arabidopsis embryogenesis.Genes Dev,15:902～911
  • 6Deshaies RJ(1999).SCF and cullin/RING-H2-based ubiquitin ligaseas.Annu Rev Cell Dev Biol,15:435～467
  • 7Dharmasiri N,Dharmasiri S,Estelle M(2005a).The F-box protein TIR1 is an auxin receptor.Nature,435:441～445
  • 8Dharmasiri N,Dharmasiri S,Weijers D,Lechner E,Yamada M,Hobbie L,Ehrismann JS,Jurgens G,Estelle M(2005b).Plant development is regulated by a family of auxin receptor F box proteins.Dev Cell,9:109～119
  • 9Dreher KA,Brown J,Saw RE,Callis J(2006).The Arabidopsis Aux/IAA protein family has diversified in degradation and auxin responsiveness.Plant Cell,18:699～714
  • 10Gray WM,Kepinski S,Rouse D,Leyser O,Estelle M(2001).Auxin regulates SCFTIR1-dependent degradation of AUX/IAA proteins.Nature,414:271～276

共引文献10

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二级引证文献26

植物生理学通讯
2009年 第11期

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