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吉西他滨联合紫杉醇治疗晚期乳腺癌20例

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摘要 目的观察吉西他滨联合紫杉醇治疗晚期乳腺癌的近期疗效和患者不良反应。方法吉西他滨1000mg/m^2静脉滴注第1,8天(第1天在紫杉醇之后用),紫杉醇150~175mg/m^2静脉滴注第1天(GT方案),21d为1个周期,治疗2个周期后评价疗效,有效者化疗4~6个周期。结果全组20例,CR0例,PR11例,SD5例,PD4例,总有效率55.0%。不良反应主要为Ⅰ~Ⅲ度白细胞及血小板减少、皮疹、脱发、轻度消化道反应及肌肉关节酸痛。结论吉西他滨联合紫杉醇治疗晚期乳腺癌疗效较好,不良反应可耐受,有较好的临床应用价值。
出处 《肿瘤研究与临床》 CAS 2009年第11期776-777,共2页 Cancer Research and Clinic
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